Welcome to ‘Microwaves in Medicinal Chemistry’
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چکیده
منابع مشابه
Fluorine in medicinal chemistry.
Since its first use in the steroid field in the late 1950s, the use of fluorine in medicinal chemistry has become commonplace, with the small electronegative fluorine atom being a key part of the medicinal chemist's repertoire of substitutions used to modulate all aspects of molecular properties including potency, physical chemistry and pharmacokinetics. This review will highlight the special n...
متن کاملChallenges in Medicinal Chemistry
The number of approved drugs for the market is decreasing in recent years and calls for more effective methods to discover a higher number of successful compound candidates. Medicinal chemistry at the forefront is challenged here but also since it provides the most time-consuming step in the drug discovery process. Medicinal chemistry has made transformations through several technological innov...
متن کاملPolyethylenimine in medicinal chemistry.
Polyethylenimine (PEI), an organic branched or linear polyamine polymer, has been successfully used in the past for DNA complexation and transfection in vitro and in vivo into several cell lines and tissues. PEI was also applied in different fields from gene therapy and several studies have emphasized the importance of this polymer in medicinal chemistry. In this brief critical review the uses ...
متن کاملFluorine in medicinal chemistry.
Fluorinated compounds are synthesized in pharmaceutical research on a routine basis and many marketed compounds contain fluorine. The present review summarizes some of the most frequently employed strategies for using fluorine substituents in medicinal chemistry. Quite often, fluorine is introduced to improve the metabolic stability by blocking metabolically labile sites. However, fluorine can ...
متن کاملWelcome to virosphere
Viruses may seem alien, but they are the most abundant and, arguably, the most important organisms on Earth. They are found just about everywhere, from oceans and forests to the people around you and, of course, in and on you as well. This world of strange, quasi-living things has been dubbed the virosphere, and it is a mysterious one – we know less about viruses than any other life form. But t...
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ژورنال
عنوان ژورنال: Future Medicinal Chemistry
سال: 2010
ISSN: 1756-8919,1756-8927
DOI: 10.4155/fmc.09.169